A List of Common Excipients for Tablet Formulation


Excipients are typically the major components of a solid dosage form and are included for a number of reasons such as to aid the manufacturing process and stability or to add functionality to the formulation.


Diluents

  • Calcium phosphate Dihydrate
  • Microcrystalline Cellulose
  • Lactose
  • Mannitol
  • Starch


Binders and Adhesives

  • Povidone (PVP)
  • Starch
  • Cellulose Derivatives (HPMC, HPC etc.)


Disintegrants

  • Crospovidone (Cross-linked PVP)
  • Croscarmellose Sodium
  • Starch


Lubricants

  • PEGs
  • Stearic acid
  • Stearic acid salts
  • Stearic acid derivatives
  • Surfactants
  • Talc
  • Waxes


Glidants

  • Cornstarch
  • Silica derivatives
  • Talc


Coating Agent

  • PVA
  • HPMC
  • Talc
  • PEG


Colors, flavors, and sweeteners

  • FD&C and D&C dyes and lakes
  • Ready to mix coating materials containing color and flavor
  • Flavors available in two forms (spray dried, oil)
  • Artificial sweeteners
  • Natural sweeteners


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